Babel-standalone was put together as part of the pretty good reactjs.net .Net implementation of react, after the 'official' version of babel-in-the-browser was killed off.
It's /really/ not intended for use in prod.
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Edit. I kinda sent off on a stream of conciseness about reactjs.net here, feel free to ignore this bit.... :D
Infact, as well made as it is and despite using reactjs.net heavily for the last couple of years, the only time i would be inclined to use it on a new app is to leverage the universal rendering, or if your react app is just freaking massive and takes forever to run a build - otherwise you may aswell just throw everything at webpack --watch via iisnode or regular 'ole vanilla node.
Then again we had to make a bunch of changes to the package itself to fully support our bundling (we don't like cassette so we made our own) and to support multiple server-side bundles, none of which are agnostic enough to warrant a PR, so upgrading reactjs.net to a more recent version is a hassle, making me slightly biased against using it ;)
Edit: more information: https://github.com/babel/babel-standalone/blob/master/README...